14 Eylül 2010 Salı

Asthma drug might assistance mixed sclerosis: study

The Multiple Sclerosis Association of America estimates that 350,000 to 400,000 Americans have MS, that has no cure. Treatments are mostly costly so insurers and patients would acquire cheap, general drug that can assistance the disease, that majority mostly affects immature adults.

Dr. Samia Khoury of Brigham and Women"s Hospital and Harvard Medical School in Boston and colleagues tested 39 patients with relapsing-remitting MS, a form of the disease that has an capricious progression.

Patients got injections of glatiramer, an MS drug sole underneath the code name Copaxone by Teva Pharmaceutical Industries Ltd.

Half got a remedy tablet and half got albuterol, sole in Europe underneath the name salbutamol.

The patients were followed and carefully thought about for a year, with tests of their blood, and scans of their brains.

Few patients had relapses. But those who got both drug had 0.09 relapses over the year on average, whilst those that got a remedy had a relapse rate of 0.37 per year, the researchers found.

Those receiving albuterol went longer prior to their initial relapse, the researchers found.

"We interpretation that diagnosis with glatiramer acetate and albuterol is well tolerated and improves clinical outcomes in patients with mixed sclerosis," Khoury"s group wrote.

Multiple sclerosis is characterized by the loss of the greasy blanket that protects haughtiness cells, called myelin. It is believed to be caused by inflammation and patients mostly have towering levels of interleukin-12.

Albuterol helps provide a obstruction of the airways called bronchospasm that is one of the dangerous symptoms of asthma, and lowers interleukin-12. It is marketed by GlaxoSmithKline, Teva and alternative makers in both tablet and inhalant form.

Teva is now fighting in U.S. sovereign justice to strengthen the obvious on Copaxone.

(Reporting by Maggie Fox; Editing by Julie Steenhuysen and Cynthia Osterman)




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